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DNA variants

Wednesday 17 November 2004

genic variants

Genic variants are more likely to alter gene function and affect disease risk than those that occur outside genes.

See also

- low allele frequency variants (LAFV)
- DNA variant annotation
- genome-wide association studies
- HapMap ENCODE
- functionally important regions
- genotyping
- gene-centric genome-wide association studies

Types

- missense variants

See also

- variants of unknown significance (VUSs)

Videos

- Variant analysis by Ingenuity

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References

- Jorgenson E, Witte JS. A gene-centric approach to genome-wide association studies. Nat Rev Genet. 2006 Nov;7(11):885-91. PMID: 17047687

- Gibson G, Dworkin I. Uncovering cryptic genetic variation. Nat Rev Genet. 2004 Sep;5(9):681-90. PMID: 15372091