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fetal hydrocephalus

DA:66

Thursday 3 July 2003

Synopsis

- 1/500 births

Etiology

- SCL circulation obstruction
- SCL reabsorption decrease
- SCL production increase

Associations

- osteochondrodysplasias (skeletal dysplasias)

  • osteogenesis imperfecta
  • achondroplasia

- chromosomal diseases

  • trisomy 21
  • inversion 9
  • monosomy 4q

- Pierre-Robin sequence
- oligohydramnios sequence
- VATER association (VACTERL association)
- Klippel-Feil syndrome
- Apert syndrome
- fetal akinesia sequence (FAS)

Types

- X-linked hydrocephaly

Mouse models:

- hy3 mice (frameshift mutation in Hydin) (12719380, 12461648)

See also

- Malformations

  • cerebrospinal malformations

Portfolio

  • Fetal hydrocephaly (21 weeks)
  • Fetal hydrocephaly (21 weeks)