Home > D. Systemic pathology > Genetic and developmental anomalies > Genetic metabolic diseases > gout

gout

Monday 23 August 2004

Digital slides

- UI:859 - Interphalangeal joint of toe - Gout tophus
- Gouty Tophi in Sesamoid Bone of Foot by Ed Euthman.

Definition: Gout is a disorder of uric-acid metabolism.

Synopsis

- gouty tophi (gouty tophus)

  • The tophus represent accumulation of monosodium urate derived from chronic hyperurecemia seen in the disorder called gout.
  • Surrounding chronic inflammatory cells, fibrosis, and foreign body giant cells can be noted.

Localization

- gouty arthritis
- intestinal gouty nodulosis (15257557)

Susceptibility loci

- 4q25 (15252757)

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