Home > E. Pathology by systems > Skin > cutaneous melanocytic tumors
cutaneous melanocytic tumors
Thursday 1 July 2004
Digital cases
UI:1831 - dermal melanocytic nevus
1. BASAL MELANOCYTE PROLIFERATION:
lentigo simplex
solar lentigo
melanotic macule (labial and genital)
PUVA lentigo
lentiginous nevus
2. MELANOCYTIC NEVI:
common nevus (junctional, compound, intradermal)
Meyerson nevus
congenital nevus
combined nevus
inverted nevus
recurrent nevus
Halo nevus
Spitz nevus (spindle and epithelioid cell nevus)
pigmented spindle cell nevus (Reed nevus)
deep-penetrating nevus (plexiform spindle cell nevus)
3. DERMAL MELANOCYTIC LESIONS (MELANOCYTOMAS):
mongolian spot
nevus of Ota, nevus of Ito
blue nevus, cellular blue nevus
dermal melanocyte hamartoma
cutaneous neurocristic hamartoma
4. ATYPICAL MELANOCYTIC LESIONS:
dysplastic nevus (atypical nevus)
5. MALIGNANT MELANOCYTIC LESIONS:
malignant melanoma
- lentigo maligna
squamo-melanocytic tumor
Diagnosis : Description / Items
periphery / circumscription
cellularity
extension in subcutis
cell shape : fusiform cells / round cells
margins : pushing margins
fasciculation
neural structures
cellular atypia
junctional activity
epidermal invasion
peripheral inflammation
necrosis
mitoses / mitotic figures
intracranial extension for scalp lesions
stromal changes
- cilated vessels
- pseudoangiomatous features
- hyaline angiopathy
- myxoid changes
- - sclerosis
- hyalinization of stroma
- interstitial edema
amelanotic changes
ballon cell change
Diagnosis : Appearnce
See also
cutaneous tumors
melanocytic tumors
References
Bastian BC, Olshen AB, LeBoit PE, Pinkel D. Classifying melanocytic tumors based on DNA copy number changes. Am J Pathol. 2003 Nov;163(5):1765-70. PMID: 14578177
Bastian BC. Understanding the progression of melanocytic neoplasia using genomic analysis: from fields to cancer. Oncogene. 2003 May 19;22(20):3081-6. PMID: 12789284
