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subepidermal blistering diseases

Wednesday 30 June 2004

MINIMALLY INFLAMMATORY

NO EPIDERMAL NECROSIS
- epidermolysis bullosa acquisita
- epidermolysis bullosa simplex, junctional, dystrophic
- bullosis diabeticorum
- porphyria cutanea tarda
- pseudoporphyria
- bullous pemphigoid, cell poor variant

EPIDERMAL NECROSIS
- toxic epidermla necrolysis
- thermal injury

LYMPHOCYTES PREDOMINATE

NECROTIC KERATINOCYTES
- lichen planus pemphigoides
- fixed drug eruption
- erythema multiforme

NO NECROTIC KERATINOCYTES
- polymorphous light eruption
- lichen sclerosus et atrophicus

EOSINOPHILS PREDOMINATE

- bullous drug eruption
- arthropod bite reaction
- herpes gestationis
- bullous pemphigoid

NEUTROPHILS PREDOMINATE

- dermatitis herpetiformis
- linear IgA bullous dermatosis
- epidermolysis bullosa acquisita
- Sweet syndrome
- bullous cutaneous lupus erythematosus
- bullous vasculitis
- cicatricial pemphigoid


Return to: cutaneous blistering diseases


references: Textbook of dermatopathology, Raymond L. Barnhill, subepidermal vesicular dermatitis, Bruce R. Smoller, p148

References

- Verdolini R, Cerio R. Autoimmune subepidermal bullous skin diseases: the impact of recent findings for the dermatopathologist. Virchows Arch. 2003 Aug;443(2):184-93. Epub 2003 Jun 11. PMID: #12802582#