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neuroendocrine tumors

Monday 28 June 2004

Digital case

- JRC:481 : High-grade neuroendocrine carcinoma (possibly anaplastic medullary carcinoma)
- JRC:1591 : Spindle cell carcinoid tumor of the lung

Classification

- thyroid medullary carcinoma
- neuroendocrine carcinoma
- paraganglioma
- parathyroid adenoma
- carcinoid tumor

  • bronchial carcinoid tumor
  • duodenal carcinoid tumor
  • ileal carcinoid tumor
  • appendiceal carcinoid tumor

Localization

- pancreatic neuroendocrine tumors
- digestive neuroendocrine tumors
- thyroid neuroendocrine tumors
- pulmonary neuroendocrine tumors

Subtypes

- multifocal neuroendocrine tumors

Grading

- Grading with Ki-67 (#22895268#)

Genetics

- 11q LOH (21%) (#15920555#)
- 16q (13%) (#15920555#)
- 18 (30%) (#15920555#)
- BRAF locus

See also

- neuroendocrine organs
- neuroendocrine markers

References

- Grading of Neuroendocrine Tumors With Ki-67 Requires High-quality Assessment Practices. Remes SM, Tuominen VJ, Helin H, Isola J, Arola J. Am J Surg Pathol. 2012 Sep;36(9):1359-63. PMID: #22895268#

- Chung DC. Cyclin D1 in human neuroendocrine tumorigenesis. Ann N Y Acad Sci. 2004 Apr;1014:209-17. PMID: #15153436#

Portfolio

  • Appendiceal carcinoid tumor
  • Appendiceal carcinoid tumor