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serine

Tuesday 1 June 2004

L-serine serves as a building block for protein synthesis and can be modified in different metabolic pathways to generate several essential compounds.

Although it is available from dietary sources, L-serine can be synthesized from 3-phosphoglycerate via 3 enzymatic steps in the phosphorylated pathway. PSAT (EC 2.6.1.52) catalyzes the second step in the pathway, conversion of 3-phosphohydroxypyruvate into 3-phosphoserine.

See also

- serine biosynthesis pathway

  • anomalies of the serine biosynthesis pathway