Home > C. Tissular pathology > chronic inflammation
Tuesday 1 June 2004
Definition: Inflammation in which mononuclear leukocytes, including lymphocytes, plasma cells (plasmocytes), and macrophages (histiocytes) predominate.
Occasional small lymphoid aggregates without germinal centers are to be expected, but presence of germinal centers is prima facie evidence of chronic inflammation.
Prominent numbers of eosinophils and mast cells, and fibrocytes with fibrosis when there is tissue repair, are often included in the overall picture of chronic inflammation.
Localization - Examples
chronic interstitial nephritis