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chronic inflammation

Tuesday 1 June 2004

Definition: Inflammation in which mononuclear leukocytes, including lymphocytes, plasma cells (plasmocytes), and macrophages (histiocytes) predominate.

Occasional small lymphoid aggregates without germinal centers are to be expected, but presence of germinal centers is prima facie evidence of chronic inflammation.

Prominent numbers of eosinophils and mast cells, and fibrocytes with fibrosis when there is tissue repair, are often included in the overall picture of chronic inflammation.

Types

- lymphocytic inflammation
- plasmacytic inflammation
- eosinophilic inflammation
- granulation tissue
- fibrosis

Localization

- chronic myocarditis
- chronic interstitial nephritis
- chronic pancreatitis
- chronic vasculitis

See also

- Inflammation

Portfolio

  • Chronic inflammation
  • Chronic interstitial nephritis
  • Cutaneous fistula complicating a chronic osteomyelitis
  • Cutaneous fistula complicating a chronic osteomyelitis