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enterocolic lymphocytic phlebitis

Wednesday 26 May 2004

Enterocolic lymphocytic phlebitis (ELP) is a rare form of vasculitis localized to the veins of the gastrointestinal tract, without evidence of systemic vasculitis.

The term was coined by Saraga et al in 1989, but a case of granulomatous phlebitis reported earlier in 1976 by Stevens et al appears to be the same entity, according to the description and pictures in the paper. Three of five cases, reported even earlier, in 1971, as part of a series on mesenteric venous thrombosis, also had lymphocytic or necrotizing phlebitis, which spared arteries.

It is characterized by a prominent lymphocytic inflammation of veins and venules of all sizes but spares the arteries. The involved vessels are found in the bowel wall and mesentery. Fibrin thrombi and fibrinoid necrosis of the walls are often present.

Associations

- anticardiolipin antibodies

References

- Wright CL, Cacala S. Enterocolic lymphocytic phlebitis with lymphocytic colitis, lymphocytic appendicitis, and lymphocytic enteritis. Am J Surg Pathol. 2004 Apr;28(4):542-7. PMID: 15087675