Tuesday 17 June 2003
Definition: Ischemia is a loss of blood supply from impeded arterial flow or reduced venous drainage in a tissue. Ischemia compromises the supply not only of oxygen, but also of metabolic substrates, including glucose (normally provided by flowing blood).
- hepatic ischemia
- renal ischemia
- digestive ischemia
- intestinal ischemia
Liang D, Dawson TM, Dawson VL. What have genetically engineered mice taught us about ischemic injury? Curr Mol Med. 2004 Mar;4(2):207-25. PMID: #15032714#
Salvemini D, Cuzzocrea S: Superoxide, superoxide dismutase and ischemic injury. Curr Opin Investig Drugs 3:886, 2002.
Sheridan AM, Bonventre JV: Cell biology and molecular mechanisms of injury in ischemic acute renal failure. Curr Opin Nephral Hypertens 9:427, 2000.