Home > C. Tissular pathology > Ischemia

Ischemia

Tuesday 17 June 2003

Digital cases

- Case 77 (HPC:77) : Hepatic ischemia in prematurity
- Case 159 (HPC:159) : Myocardial infarction

Definition: Ischemia is a loss of blood supply from impeded arterial flow or reduced venous drainage in a tissue. Ischemia compromises the supply not only of oxygen, but also of metabolic substrates, including glucose (normally provided by flowing blood).

Localization

- cerebral ischemia
- limbs ischemia
- myocardic ischemia
- visceral ischemia

  • hepatic ischemia
  • renal ischemia
  • digestive ischemia
    • intestinal ischemia

See also

- ischemic necrosis

References

- Liang D, Dawson TM, Dawson VL. What have genetically engineered mice taught us about ischemic injury? Curr Mol Med. 2004 Mar;4(2):207-25. PMID: #15032714#

- Salvemini D, Cuzzocrea S: Superoxide, superoxide dismutase and ischemic injury. Curr Opin Investig Drugs 3:886, 2002.

- Sheridan AM, Bonventre JV: Cell biology and molecular mechanisms of injury in ischemic acute renal failure. Curr Opin Nephral Hypertens 9:427, 2000.