- Human pathology

Home > E. Pathology by systems > Skin > cutaneous leishmaniasis

cutaneous leishmaniasis

Thursday 20 May 2004

Definition: Cutaneous leishmaniasis, caused by Leishmania major, Leishmania mexicana, and Leishmania braziliensis, is a relatively mild, localized disease consisting of a single ulcer on exposed skin.


- Macroscopy / cutaneous lesion

- Microscopy : amastigones within histiocytes; kinetoplast;

The lesion (often called tropical sore) begins as an itching papule surrounded by induration, changes into a shallow and slowly expanding ulcer with irregular borders, and usually heals by involution within 6 months without treatment.

On microscopic examination, the lesion is granulomatous, usually with many giant cells and few parasites.