tumoral architectural pattern

Types

 trabecular pattern (trabecular tumors)
 papillary pattern (papillary tumors)
 tubular pattern (tubular tumors)
 tubulopapillary pattern (tubulopapillary tumors)
 diffuse pattern (compact pattern or solid pattern)
 scleronodular pattern (scleronodular tumors)
 herringbone pattern
 plexiform pattern (plexiform tumors)
 hemangiopericytic pattern
 angular pattern
 lobular pattern (lobular tumors)

• myxoid and lobular tumors

 alveolar pattern (alveolar tumors)
 glandular pattern (glandular tumors)

• acinar pattern (acinar tumors)
• adenomatous pattern (adenomatous tumors)

 dual composition (biphasic tumors)
 circular or oval formations
 microacini
 cribriform
 rossettes
 cylindromatous differentiation
 myxoid tumors

• myxoid and lobular tumors

Tumoral formations

 whorl formations
 circular formations
 oval formations
 tumoral clefts
 tumoral laceworks
 tumoral bone formation
 tumoral calcifications

Areas

 spindle cell areas (spindle cell tumors)
 myxoid areas (myxoid tumors)

• myxoid and lobular tumors

Appearance of cellular sheets

 sheets of small round cells
 sheets of small cells with eccentric nuclei
 sheets of large round cells
 sheets of large cells with eccentric nuclei and abundant eosinophilic cytoplasm (myoid cells)
 sheets of spindle cells
 sheets of strap cells
 sheets of stellate cells

Tumoral architectural patterns (examples)

 papillary pattern

• thyroid papillary carcinoma
• renal papillary carcinoma

 tubular pattern

• tubulous adenoma
• adenocarcinomas

 trabecular pattern

• endocrine carcinomas
  • carcinoid tumors
  • paragangliomas (pheochromocytoma)

 solid pattern or compact pattern

 scleronodular pattern

• scleronodular Hodgkin lymphoma

 herringbone pattern

• fibrosarcomas
• synovialosarcoma

 hemangiopericytomatous pattern

• infantile myofibromatosis

See also

 microarchitecture

References

 Potter JD. Morphogens, morphostats, microarchitecture and malignancy. Nat Rev Cancer. 2007 Jun;7(6):464-74. PMID: #17522715#

Books

 Tumors: An atlas of differential diagnosis, by Cyril Toker. University Park Press, Baltimore, 1983. ISBN: 0839118120