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tumoral architectural pattern

Thursday 20 May 2004

tumoral architectural patterns, tumoral architecture, tumoral pattern

Types

- trabecular pattern (trabecular tumors)
- papillary pattern (papillary tumors)
- tubular pattern (tubular tumors)
- tubulopapillary pattern (tubulopapillary tumors)
- diffuse pattern (compact pattern or solid pattern)
- scleronodular pattern (scleronodular tumors)
- herringbone pattern
- plexiform pattern (plexiform tumors)
- hemangiopericytic pattern
- angular pattern
- lobular pattern (lobular tumors)

  • myxoid and lobular tumors

- alveolar pattern (alveolar tumors)
- glandular pattern (glandular tumors)

  • acinar pattern (acinar tumors)
  • adenomatous pattern (adenomatous tumors)

- dual composition (biphasic tumors)
- circular or oval formations
- microacini
- cribriform
- rossettes
- cylindromatous differentiation
- myxoid tumors

  • myxoid and lobular tumors

Tumoral formations

- whorl formations
- circular formations
- oval formations
- tumoral clefts
- tumoral laceworks
- tumoral bone formation
- tumoral calcifications

Areas

- spindle cell areas (spindle cell tumors)
- myxoid areas (myxoid tumors)

  • myxoid and lobular tumors

Appearance of cellular sheets

- sheets of small round cells
- sheets of small cells with eccentric nuclei
- sheets of large round cells
- sheets of large cells with eccentric nuclei and abundant eosinophilic cytoplasm (myoid cells)
- sheets of spindle cells
- sheets of strap cells
- sheets of stellate cells

Tumoral architectural patterns (examples)

- papillary pattern

  • thyroid papillary carcinoma
  • renal papillary carcinoma

- tubular pattern

  • tubulous adenoma
  • adenocarcinomas

- trabecular pattern

  • endocrine carcinomas
    • carcinoid tumors
    • paragangliomas (pheochromocytoma)

- solid pattern or compact pattern

- scleronodular pattern

  • scleronodular Hodgkin lymphoma

- herringbone pattern

  • fibrosarcomas
  • synovialosarcoma

- hemangiopericytomatous pattern

  • infantile myofibromatosis

See also

- microarchitecture

References

- Potter JD. Morphogens, morphostats, microarchitecture and malignancy. Nat Rev Cancer. 2007 Jun;7(6):464-74. PMID: #17522715#

Books

- Tumors: An atlas of differential diagnosis, by Cyril Toker. University Park Press, Baltimore, 1983. ISBN: 0839118120