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bilirubin

Tuesday 4 May 2004

Bilirubin is the normal major pigment found in bile. It is derived from hemoglobin but contains no iron. Its normal formation and excretion are vital to health, and jaundice is a common clinical disorder caused by excesses of this pigment within cells and tissues. Bilirubin is a potent antioxidant but can be toxic at high concentrations.

Pathology

- bilirubin metabolism disorders

Features

- bilirubin metabolism

References

- Rigato I, Ostrow JD, Tiribelli C. Bilirubin and the risk of common non-hepatic diseases. Trends Mol Med. 2005 Jun;11(6):277-83. PMID: #15949769#

- Ostrow JD, Pascolo L, Brites D, Tiribelli C. Molecular basis of bilirubin-induced neurotoxicity. Trends Mol Med. 2004 Feb;10(2):65-70. PMID: #15102359#