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giant cell hepatitis

Sunday 2 May 2004

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Etiology

- neonatal giant cell hepatitis
- post-infantile giant cell hepatitis
- infectious giant cell hepatitis

- parasitic hepatitis

- cholestasis

- chromosomal anomalies

- genetic metabolic disorders

  • alpha-1-antitrypsin deficiency (1)
    -* galactosemia
  • Niemann-Pick disease
  • Gaucher disease
  • mucolipidosis
  • cerebrohepatorenal syndrome (Zellweger’s syndrome)
  • acute tyrosinemia

- giant cell hepatitis with autoimmune hemolytic anemia (GCHAIHA)
- autoimmune hepatitis type II (LKM1+)
- erythematosus lupus (systemic lupus) ΒΈ

According to age

- neonatal giant cell hepatitis
- infantile giant cell hepatitis
- postinfantile giant cell hepatitis

Associations

- neonatal hemochromatosis
- autoimmune hemolytic anemia (GCHAIHA)

See also

- hepatocytic giant cell transformation

References

- Neonatal giant cell hepatitis: histological and etiological findings. Torbenson M, Hart J, Westerhoff M, Azzam RK, Elgendi A, Mziray-Andrew HC, Kim GE, Scheimann A. Am J Surg Pathol. 2010 Oct;34(10):1498-503. PMID: 20871223

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