Home > D. Systemic pathology > Infectious diseases > Mycobacterium sp.

Mycobacterium sp.

Friday 23 April 2004

mycobacteria, mycobacterias

Bacteria in the genus Mycobacterium are slender, aerobic rods that grow in straight or branching chains. Mycobacterium have a waxy cell wall composed of mycolic acid, which makes them acid fast, meaning they will retain stains even on treatment with a mixture of acid and alcohol. Mycobacteria stain weakly positive with Gram stain.

Tuberculosis

Mycobacterium tuberculosis is responsible for most cases of tuberculosis; the reservoir of infection is humans with active tuberculosis.

Oropharyngeal and intestinal tuberculosis contracted by drinking milk contaminated with Mycobacterium bovis is rare in developed nations, but it is still seen in countries that have tuberculous dairy cows and unpasteurized milk.

Pathology

- mycobacterial pneumonitis
- mycobacterial adenitis
- mycobacterial meningitis
- mycobacterial osteitis
- mycobacterial spindle cell pseudotumor (mycobacterial pseudotumor)

References

- Nguyen L, Pieters J. The Trojan horse: survival tactics of pathogenic mycobacteria in macrophages. Trends Cell Biol. 2005 May;15(5):269-76. PMID: 15866031

- Russell DG. Mycobacterium and Leishmania: stowaways in the endosomal network. Trends Cell Biol. 1995 Mar;5(3):125-8. PMID: 14732168

Portfolio

  • Ziehl–Neelsen stain (acid-fast stain) - Courtesy of Dr Yale Rosen
  • Ziehl–Neelsen stain (acid-fast stain) - Courtesy of Dr Yale Rosen
  • Ziehl–Neelsen stain (acid-fast stain) - Courtesy of Dr Yale Rosen
  • Ziehl–Neelsen stain (acid-fast stain) - Courtesy of Dr Yale Rosen
  • Ziehl–Neelsen stain (acid-fast stain) - Courtesy of Dr Yale Rosen
  • Ziehl–Neelsen stain (acid-fast stain) - Courtesy of Dr Yale Rosen