Home > E. Pathology by systems > Genital system > Fetus and annexes > Embryo and fetus > Hydrops

Hydrops

Thursday 22 April 2004

SYnopsis

- diffuse cutaneous edema
- cystic hygroma
- serous effusions

  • pleural effusion
  • pericardial effusion
  • peritoneal effusion

Etiology - Associations

Short list

- hematological disorders
- cardiac anomalies
- intrathoracic anomalies
- vascular anomalies
- muscular anomalies
- skeletal anomalies
- urogenital anomalies
- gastrointestinal anomalies
- fetal tumors
- genetic metabolic diseases (inborn errors of metabolism)
- chromosomal diseases
- fetal infections
- maternal diseases

Extended list

- hematological disorders

  • inherited
  • acquired

- cardiac anomalies

  • cardiac malformations
  • cardiac diseases
  • cardiac tumors
  • cardiac arrhytmias
  • myocarditis

- intrathoracic compression

  • congenital pulmonary airway malformations (CPAMs or CCAMs)
  • pulmonary sequestration
  • diaphragmatic hernia
  • intrathoracic tumors

- laryngotracheal anomalies

  • tracheal atresia
  • tracheobronchomalacia
  • laryngeal atresia
  • laryngeal stenosis

- vascular anomalies

  • fetal hemangiomas
  • placental hemangiomas
  • calcific arteriopathy
  • pulmonary lymphangiectasia
  • diffuse lymphangiectasia
  • acardiac monozygous twin pregnancy
  • vena caval thrombus
  • coronary artery thrombus
  • fetal entanglement umbilical cord
  • meningeal angiodysplasia

- skeletal anomalies (genetic osteochondrodysplasias)

  • achondrogeneses
    • achondrogenesis type 1 (MIM.200600 and MIM.600972)
    • achondrogenesis type 2 (MIM.200610) (COL2A1 mutations)
    • achondrogenesis type 3 (MIM.200710)
  • Ellis-van Creveld syndrome (chondroectodermal dysplasia) (MIM.225500) (EVC1 and EVC2 mutations)
  • short ribs-polydactyly syndrome type 1 (Saldino-Noonan syndrome) (MIM.263530)
  • osteogenesis imperfecta (MIM.166200) (COL1A1 and COL1A2 mutations)
  • Jeune syndrome (Jeune asphyxiating thoracic dystrophy) (MIM.208500)
  • thanotophoric dysplasia (thanatophoric nanism) (MIM.187600) (FGFR3 mutations)
  • Mohr syndrome (orofaciodigital syndrome type 2) (MIM.252100)
  • Greenberg dysplasia (MIM.215140) (LBR mutations)
  • campomelic dysplasia

- fetal motility anomalies

  • multiple pterygium syndrome (MIM.265000)
  • popliteal pterygium syndrome (MIM.119500) (IRF6 mutations)
  • Neu-Laxova syndrome (MIM.256520)
  • Pena-Shokeir syndrome (MIM.208150)
  • myotonic dystophy (MIM.160900)
  • arthrogryposis

- cerebral anomalies

  • hydrocephaly
  • holoprosencephaly

- amniotic anomalies

  • amniotic band syndrome (ABS)

- systemic genetic anomalies

  • Noonan syndrome
  • Simpson-Golabi-Behmel syndrome (#8599356#)

- urogenital anomalies

- digestive malformations

  • esophageal atresia
  • jejunal atresia
  • small intestinal volvulus
  • meconial ileus +/- meconial peritonitis
  • intestinal infarction
  • intestinal obstruction

- hepatic anomalies

  • hepatitis
  • hepatic necrosis
  • fetal cirrhosis
  • neonatal hemochromatosis

- fetal tumors

- genetic metabolic diseases (inborn errors of metabolism)

  • Gaucher disease
  • mucopolysaccharidosis
  • Günther disease
  • Niemann-Pick disease
  • gangliosidosis

- chromosomal diseases

  • monosomy X (45, XO)
  • trisomy 21
  • trisomy 18
  • trisomy 13
  • triploidy
  • unbalanced translocation t(3;17)

- fetal infections

  • Parvovirus B19 fetal infection (#9670826#)
  • fetal CMV infection
  • Herpesvirus I
  • rubella virus
  • toxoplasmosis
  • fetal syphilis
  • Coxsackievirus
  • parvovirus
  • adenovirus
  • listeriosis
  • Mycoplasma

- hypoalbuminemia

- maternal diseases

  • dysimmunity (connectivitis)
  • maternal diabetes mellitus
  • maternal anemia
  • choriocarcinoma

Portfolio

  • Hydrops fetalis
  • Hydrops fetalis
  • Hydrops fetalis
  • Fetal ascites in hydrops fetalis (fetus, 19 weeks)
  • Fetal ascites in hydrops fetalis (fetus, 19 weeks)
  • Fetal ascites in hydrops fetalis (fetus, 19 weeks)