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bone tumors

Friday 16 April 2004

Semiological classification

- bone-forming tumors of bones
- cartilage-forming tumors of bones
- fibrous tumors of bones (fiber-forming osseous tumors)
- nonmatrix-producing bone tumors

Developped semiological classification

- bone-forming tumors of bones

  • Reactive or Post-Traumatic Lesions that may be Mistaken for Malignant Tumors
    • Florid Reactive Periostitis
    • Subungual (Dupuytren) Exostosis
    • Bizarre Parosteal Osteochondromatous Proliferation (Nora’s Lesion)
  • Benign Tumors
    • Bone Island (Solitary Enostosis)
    • Osteopoikilosis
    • Melorheostosis
    • Osteopathia Striata (Voorhoeve’s Disease)
    • Surface Osteomas of the Cranium, Facial Bones, and Other Bones
    • Osteoid Osteoma
    • Osteoblastoma
  • Malignant Tumors
    • Osteosarcoma (Osteogenic Sarcoma)
    • Paget’s Sarcoma
    • Radiation Sarcoma

- cartilage-forming tumors of bones

  • Benign Tumors
    • Osteochondroma (Osteocartilaginous Exostosis)
    • Multiple Osteochondromas (Hereditary Multiple Osteocartilaginous Exostoses)
    • Dysplasia Epiphysealis Hemimelica (Osteochondroma of the Epiphysis; Trevor’s Disease)
    • Enchondromatosis (Ollier’s Disease)
  • Benign Neoplasms
    • Enchondroma
    • Juxtacortical Chondroma (Periosteal Chondroma)
    • Chondroblastoma
    • Chondromyxoid Fibroma
    • Fibromyxoma, 416
  • Malignant Neoplasms
    • Intramedullary Chondrosarcoma
    • Mesenchymal Chondrosarcoma
    • Clear Cell Chondrosarcoma
    • Chordoma

- fibrous tumors of bones (fiber-forming osseous tumors)

  • Reactive or Post-Traumatic Tumors
    • Periosteal ‘Desmoid’ Tumors
    • Nonossifying Fibroma (Fibrous Cortical Defect; Benign Fibrous Histiocytoma)
  • Benign Neoplasms
    • Fibrous Dysplasia (Fibro-Osseous Dysplasia; Fibro-Osseous Lesion)
    • Liposclerosing Myxofibrous Tumor
    • Osteofibrous Dysplasia (Differentiated Adamantinoma)
    • Desmoplastic Fibroma, 441
  • Malignant Neoplasms
    • Fibrosarcoma
    • Malignant Fibrous Histiocytoma
    • Adamantinoma of Long Bones

- nonmatrix-producing bone tumors

  • Benign Nonmatrix-Producing Bone Tumors
    • Reactive or Post-Traumatic Tumors
      • Epidermoid Inclusion Cyst
      • Ganglion Cyst of Bone
      • Unicameral Bone Cyst (Solitary Cyst; Simple Bone Cyst)
  • Benign Tumors Including Neoplasms
    • Aneurysmal Bone Cyst
    • Giant Cell Reparative Granuloma (Solid Aneurysmal Bone Cyst)
    • Hemangioma of Bone
    • Skeletal Hemangiomatosis/Lymphangiomatosis (Cystic Angiomatosis of Bone, Lymphangiectasis of Bone)
    • Eosinophilic Granuloma (Langerhans’ Cell Histiocytosis)
    • Lipid Granulomatosis of Bone (Chester-Erdheim Disease)
    • Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease),
    • Systemic Mastocytosis
    • Giant Cell Tumor
    • Lipoma of Bone
  • Malignant Nonmatrix-Producing Bone Tumors
    • Ewing’s Sarcoma (Primitive Neuroectodermal Tumor)
    • Immunohematopoietic Neoplasms
      • Primary Non-Hodgkin’s Lymphoma
      • Hodgkin’s Disease
      • Leukemia
      • Multiple Myeloma
      • Solitary (Localized) Myeloma (Plasmacytoma)
    • Vascular Neoplasms
      • Well-Differentiated Endothelial Neoplasms
      • Poorly Differentiated Endothelial Neoplasms
      • Hemangiopericytoma
    • Metastatic Cancer

WHO classification 2002

- cartilage tumors of bone
- osteogenic tumors of bone
- fibrogenic tumors of bone
- fibrohistiocytic tumors of bone
- Ewing sarcoma of bone/primitive neuroectodermal tumor of bone
- hematopoietic tumors of bone
- giant cell tumor of bones
- notochordal tumors of bone
- vascular tumors of bone
- smooth muscle tumors of bone
- lipogenic tumors of bone
- neural tumors of bone
- miscellaneous tumors of bone

Differential diagnosis

- osseous tumor-like conditions

Links

- bonetumor.org
- Benign, Malignant and Metastatic Bone Tumors by Daria Brooks, MD; James Jelinek, MD; Dhruv Kumar, MD at WCI, DC

References

- Abdul-Karim FW, Bauer TW, Kilpatrick SE, Raymond KA, Siegal GP; Association of Directors of Anatomic and Surgical Pathology. Recommendations for the reporting of bone tumors. Association of Directors of Anatomic and Surgical Pathology. Hum Pathol. 2004 Oct;35(10):1173-8. PMID: #15492983#

Portfolio

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