Home > E. Pathology by systems > Digestive system > Liver > centrilobular necrosis

centrilobular necrosis

Tuesday 13 April 2004

Types

- centrilobular hepatocellular ballooning
- centrilobular focal liver cell necrosis
- centrilobular sinusoidal congestion
- centrilobular drop-out
- centrilobular hemorrhagic necrosis
- confluent lobular necrosis

Etiology

- acute liver allograft rejection (acute cellular rejection)

  • acute centrilobular rejection
    • centrilobular necrosis in liver allograft
    • centrilobular lymphocytic infiltration

- autoimmune hepatitis
- hepatic veno-occlusive disease
- toxics

  • acetaminophen intoxication
  • Amanita mushroom poisoning

See also

- hepatic lesions

  • centrilobular lesions

References

- Centrilobular necrosis in children after combined liver and small bowel transplantation. Lacaille F, Canioni D, Fournet JC, Revillon Y, Cezard JP, Goulet O. Transplantation. 2002 Jan 27;73(2):252-7. PMID: #11821740#

Portfolio

  • Confluent centrilobular necrosis in hepatic veno-occlusive disease
  • Confluent centrilobular necrosis in hepatic veno-occlusive disease
  • Confluent centrilobular necrosis in hepatic veno-occlusive disease