Home > E. Pathology by systems > Skin > pilomatricoma

pilomatricoma

Thursday 18 March 2004

Digital cases

- JRC:10845 : Pilomatrixoma.
- JRC:10847 : Pilomatrixoma.
- pathxchange #2207.

Variants

- pilomatrixoma with only germinative-matrical cells (see photos) ((with the passage of time, the number of basaloid cells decreases progressively, eventually to be replaced by ghost cells)
- lymphangiectatic variant of pilomatricoma (15324397)
- pilomatricoma with a bullous appearance (15268712)

Differential diagnosis

- basal cell carcinoma
- pilomatrical carcinoma
- melanocytic matricoma

Etiology

- some cases of pilomatrixoma are caused by mutation in the beta-catenin gene (CTNNB1) (MIM.116806) (12575848, 11472567, 11004631, 10192393)

Epidemiological forms

- multiple pilomatricomas (pilomatricomatosis or pilomatrixomata) (8747580, 12702091)
- familial pilomatricomas (14984583, 12702091)

Associations

- multiple pilomatricomas and myotonic dystrophy (10434894, 3175462, 11978577, 8891827)
- multiple pilomatricomas and trisomy 9 (11834859)
- peripheral schannoma (15640970)
- multiple pilomatricomas in Rubinstein-Taybi syndrome (15324407, 8170843)
- Turner syndrome (10640845)

See also

- cutaneous lesions
- cutaneous tumors

  • cutaneous adnexal tumors

Portfolio

  • Pilomatrixoma. Section. Macroscopy
  • Pilomatrixoma. Slide. HE x1
  • Basaloid pilomatricoma
  • Basaloid pilomatricoma
  • Basaloid pilomatricoma
  • Basaloid pilomatricoma
  • Basaloid pilomatricoma
  • Basaloid pilomatricoma
  • Pilomatricoma
  • Pilomatrixoma
  • Pilomatrixoma
  • Pilomatrixoma
  • Pilomatrixoma
  • Pilomatrixoma
  • Pilomatrixoma