Home > E. Pathology by systems > Skin > pilomatricoma

pilomatricoma

Thursday 18 March 2004

Digital cases

- JRC:10845 : Pilomatrixoma.
- JRC:10847 : Pilomatrixoma.
- pathxchange #2207.

Variants

- pilomatrixoma with only germinative-matrical cells (see photos) ((with the passage of time, the number of basaloid cells decreases progressively, eventually to be replaced by ghost cells)
- lymphangiectatic variant of pilomatricoma (#15324397#)
- pilomatricoma with a bullous appearance (#15268712#)

Differential diagnosis

- basal cell carcinoma
- pilomatrical carcinoma
- melanocytic matricoma

Etiology

- some cases of pilomatrixoma are caused by mutation in the beta-catenin gene (CTNNB1) (MIM.116806) (#12575848#, #11472567#, #11004631#, #10192393#)

Epidemiological forms

- multiple pilomatricomas (pilomatricomatosis or pilomatrixomata) (#8747580#, #12702091#)
- familial pilomatricomas (#14984583#, #12702091#)

Associations

- multiple pilomatricomas and myotonic dystrophy (#10434894#, #3175462#, #11978577#, #8891827#)
- multiple pilomatricomas and trisomy 9 (#11834859#)
- peripheral schannoma (#15640970#)
- multiple pilomatricomas in Rubinstein-Taybi syndrome (#15324407#, #8170843#)
- Turner syndrome (#10640845#)

See also

- cutaneous lesions
- cutaneous tumors

  • cutaneous adnexal tumors

Portfolio

  • Pilomatrixoma. Section. Macroscopy
  • Pilomatrixoma. Slide. HE x1
  • Basaloid pilomatricoma
  • Basaloid pilomatricoma
  • Basaloid pilomatricoma
  • Basaloid pilomatricoma
  • Basaloid pilomatricoma
  • Basaloid pilomatricoma
  • Pilomatricoma
  • Pilomatrixoma
  • Pilomatrixoma
  • Pilomatrixoma
  • Pilomatrixoma
  • Pilomatrixoma
  • Pilomatrixoma