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osteochondroma

Thursday 18 March 2004

Digital case (Digital slides)

- HPC:396 : Osteochondroma

Cytogenetics

- loss of distal 8q (11793371)

Predisposition

- multiple osteochondromas (or hereditary multiple exostoses (HME) or osteochnondromatosis)

  • type 1 (MIM.133700): EXT1 germline mutations
  • type 2 (MIM.133701): EXT2 germline mutations

References

- Tallini G, Dorfman H, Brys P, Dal Cin P, De Wever I, Fletcher CD, Jonson K, Mandahl N, Mertens F, Mitelman F, Rosai J, Rydholm A, Samson I, Sciot R, Van den Berghe H, Vanni R, Willen H. Correlation between clinicopathological features and karyotype in 100 cartilaginous and chordoid tumours. A report from the Chromosomes and Morphology (CHAMP) Collaborative Study Group. J Pathol. 2002 Feb;196(2):194-203. PMID: 11793371

Portfolio

  • Osteochondroma. Section. Macroscopy
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Femoral osteochondroma
  • Femoral osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma
  • Osteochondroma