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NPM1

MIM.164040 5q35

Thursday 11 March 2004

Pathology

- fusion gene NPM1/ALK in anaplastic large cell lymphoma (ALCL) with t(2;5)(p23;q35)

- fusion gene NPM1/MLF1

  • in acute myeloid leukemia with t(3;5)(q25;q35) (NPM1-mutated acute myeloid leukemia)
  • in myelodysplasia with t(3;5)(q25;q35)

Portfolio

  • t(2;5)(p23;q35) creating NPM1/ALK fusion gene