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ovarian teratoma

Wednesday 10 March 2004

Digital cases (Digital slides)

- HPC:387 : Necrotic ovarian cyst. Necrotic mature ovarian teratoma ?
- JRC:13319 : Struma ovarii.

Definition: Teratomas are the most common germ cell tumor (GCT) of the ovary and include several types with a range of clinical behavior. As in testicular teratomas, they may be benign, malignant or a component of a mixed GCT.

In the testis, data support separate pathogeneses for prepubertal and postpubertal teratomas, with derivation of the former from a nontransformed germ cell and the latter from differentiation of a nonteratomatous, malignant GCT.

The absence of cytogenetic abnormalities (including isochromosome 12p (i(12p)) in mature ovarian teratomas suggests that they may be analogous to prepubertal testicular teratomas.

Types

- ovarian mature teratoma (ovarian mature cystic teratoma)

  • ovarian multitissular mature teratoma
  • ovarian dermoid cysts

- ovarian immature teratoma

Case records

- pathxchange.org #10261

See also

- ovarian germ cell tumors (OGCTs)

  • ovarian mixed germ cell tumors (OMGCTs)

References

- Analysis of ovarian teratomas for isochromosome 12p: evidence supporting a dual histogenetic pathway for teratomatous elements. Poulos C, Cheng L, Zhang S, Gersell DJ, Ulbright TM. Mod Pathol. 2006 Jun;19(6):766-71. PMID: 16547466 (Free)

- Evidence of parthenogenetic origin of ovarian teratoma: case report. Oliveira FG, Dozortsev D, Diamond MP, Fracasso A, Abdelmassih S, Abdelmassih V, Gonçalves SP, Abdelmassih R, Nagy ZP. Hum Reprod. 2004 Aug;19(8):1867-70. PMID: 15192066

Portfolio

  • Ovarian immature teratoma
  • Neuroectodermal tissue in immature ovarian teratoma (6 years)
  • Neuroectodermal tissue in immature ovarian teratoma (6 years)
  • Cuteaneous tissue in immature ovarian teratoma (6 years)
  • Ciliated epithelium in immature ovarian teratoma (6 years)
  • Glandular tissue in immature ovarian teratoma (6 years)
  • Ovarian cystic mature teratoma
  • Ovarian cystic mature teratoma
  • Ovarian mature teratoma