Monday 8 March 2004, by
thickening of glomerular basal membranes
subepithelial immune deposits
no increase in mesangial cell numbers
diffuse granular deposits along the GBM
positivity for lgG and often C3 (sometimes low level of staining for IgM or IgA).
early subepithelial deposits
M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. Beck LH Jr, Bonegio RG, Lambeau G, Beck DM, Powell DW, Cummins TD, Klein JB, Salant DJ. N Engl J Med. 2009 Jul 2;361(1):11-21. PMID: 19571279