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atypical glands

Monday 22 August 2022


- prostatic atypical glands

The phrase "atypical glands suspicious for but not diagnostic of malignancy" (also known as "atypical small acinar proliferation" ASAP) is not a distinct pathologic diagnosis but rather an expression of diagnostic uncertainty applied in a variety of situations including:
- partially sampled focus of cancer,
- atypical glands at the edge of a core,
- artifacts introduced by poor histology (poor fixation, thick sections, suboptimal staining),
- atypical glands adjacent to high-grade PIN,
- atypical glands adjacent to inflammation,
- benign mimics of cancer with atypical features.