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Schneiderian papilloma

Sunday 28 February 2021

Definition : Schneiderian papillomas are benign neoplasms that are associated with three key characteristics: tendency to recur, capacity for local destruction, and association with squamous cell carcinoma.

They are classified into inverting, fungiform, and oncocytic varieties. The inverting and fungiform varieties are the most common, and the inverting variety has the highest rate of association with malignancy.

The inverting and oncocytic varieties are classically found on the lateral nasal wall with extension into the adjacent sinuses.

The fungiform lesion is typically found on the nasal septum. Treatment of these lesions is primarily surgical, with rather aggressive surgery mandated in most cases. There may be a limited role for radiation therapy and close follow-up of these patients is mandatory.

These neoplasms arise from a unique area of the respiratory epithelium, termed the schneiderian mucosa.