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hyaline cell–rich chondroid syringoma

Sunday 8 November 2020

Definition : Hyaline cell–rich chondroid syringoma is a rare benign variant of chondroid syringoma composed of cells with eosinophilic hyaline cytoplasm and plasmacytoid features, the origin of which remains elusive.

Although very few cases have been reported in literature, it is important to be aware of this entity so as to avoid misdiagnosis on histopathological examination.

Differential diagnosis

- May demonstrate atypical cells raising concern for a variety of malignant
neoplasms:

- Although atypical cells may be present, the remainder of the
histopathological features are reassuring: