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membrane trafficking

Monday 9 June 2003

Membrane traffic occurs by vesicular transport between successive compartments of the secretory pathway.

Coat complexes function to collect cargo from donor membranes and deform them to generate transport vesicles with a diameter of 60-80 nm.

Anomalies of membrane traffic

- impaired membrane trafficking
- defective ether lipid biosynthesis (11152660)
- mutations in vesicle-associated proteins

See also

- VAPs


- Palmer KJ, Stephens DJ. Biogenesis of ER-to-Golgi transport carriers: complex roles of COPII in ER export. Trends Cell Biol. 2004 Feb;14(2):57-61. PMID: 15106609

- Strickland LI, Burgess DR. Pathways for membrane trafficking during cytokinesis. Trends Cell Biol. 2004 Mar;14(3):115-8. PMID: 15055200

- Boes M, Cuvillier A, Ploegh H. Membrane specializations and endosome maturation in dendritic cells and B cells. Trends Cell Biol. 2004 Apr;14(4):175-83. PMID: 15066635