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COL1A1-PDGFB-associated uterine fibrosarcoma

Friday 8 November 2019

COL1A1-PDGFB fusion

NTRK-rearranged uterine fibrosarcoma

References

- The histologic spectrum of soft tissue spindle cell tumors with NTRK3 gene rearrangements. Suurmeijer AJ, Dickson BC, Swanson D, Zhang L, Sung YS, Huang HY, Fletcher CD, Antonescu CR. Genes Chromosomes Cancer. 2019 Nov;58(11):739-746. doi : 10.1002/gcc.22767 PMID: 31112350

- Uterine and vaginal sarcomas resembling fibrosarcoma: a clinicopathological and molecular analysis of 13 cases showing common NTRK-rearrangements and the description of a COL1A1-PDGFB fusion novel to uterine neoplasms.. Croce S, Hostein I, Longacre TA, Mills AM, PĂ©rot G, Devouassoux-Shisheboran M, Velasco V, Floquet A, Guyon F, Chakiba C, Querleu D, Khalifa E, Mayeur L, Rebier F, Leguellec S, Soubeyran I, McCluggage WG. Mod Pathol. 2019 Jul;32(7):1008-1022. doi : 10.1038/s41379-018-0184-6 PMID: 30877273