Home > A. Molecular pathology > ADRB1
ADRB1
Monday 2 September 2019
Pathology
A mutation in ADRB1 leads to natural short sleep trait in humans
Mice engineered with same mutation have similar short sleep behavior as humans
Activity of dorsal pons ADRB1+ neurons associates with REM sleep and wakefulness
Mutation increases the population activity of dorsal pons ADRB1+ neurons
References
A Rare Mutation of β1-Adrenergic Receptor Affects Sleep/Wake Behaviors. 2019
doi.org:10.1016/j.neuron.2019.07.026.