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benign fusiform cell tumors

Tuesday 30 April 2019

Benign Spindle Cell Lesions

Spindle cell lesions cover a wide spectrum of diseases ranging from reactive tumor-like lesions to high-grade malignant tumors.

The recognition of the benign spindle cell tumor-like lesions (nodular fasciitis; reactive spindle cell nodule after biopsy, inflammatory pseudotumor/inflammatory myofibroblastic tumor; fascicular variant of pseudoangiomatous stromal hyperplasia) and tumors (myofibroblastoma, benign fibroblastic spindle cell tumor, leiomyoma, schwannoma, spindle cell lipoma, solitary fibrous tumor, myxoma) is crucial to avoid confusion with morphologically similar but more aggressive bland-appearing spindle cell tumors, such as desmoid-type fibromatosis, low-grade (fibromatosis-like) spindle cell carcinoma, low-grade fibrosarcoma/myofibroblastic sarcoma and dermatofibrosarcoma protuberans.

Paywall references

- Differential Diagnosis of Benign Spindle Cell Lesions. Magro G. Surg Pathol Clin. 2018 Mar;11(1):91-121. doi : 10.1016/j.path.2017.09.005 PMID: 29413661