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anaplastic thyroid carcinoma

Saturday 17 June 2017

Molecular biology

Mutations in anaplastic thyroid carcinoma: p53 (70%), beta-catenin (60%) and ras (50%). If the carcinoma has BRAF V600E, then it is arising from papillary thyroid carcinoma.

Variants

- anaplastic thyroid carcinoma with osteoclast-type giant cells
- rhabdoid anaplastic thyroid carcinoma