lymphoblastic lymphomas

Digital cases

 HPC:187 (HPC:187) : T-cell lymphoblastic lymphoma
 HPC:344 : T-cell lymphoblastic lymphoma

Subtypes

 precursor T lymphoblastic lymphoma (surface CD3+) (80%)

 precursor B lymphoblastic lymphoma (CD20+, CD19+ or CD79a+)

• B-cell lymphoblastic lymphoma represents approximately 15% of all cases of lymphoblastic lymphoma.
• B-cell lymphoblastic lymphoma is most common in older children and young adults.

 non-B, non-T lymphoblastic lymphoma (B cell marker- and surface CD3-) (5%)

• CD7+ stem cell lymphoma (CD7+SCL) [CD4-, CD7+, CD33+/-, CD56-]
• blastic natural killer cell lymphoma (B-NKL) [CD4-, CD7+/-, CD33-, CD56+, CD123-]
• myeloid/NK precursor cell leukemia (M/NKL) [CD4-, CD7+, CD33+, CD56+], and 4)
• CD4+ CD56+ hematodermic malignancy (CD4+ CD56+) type [CD4+, CD7+/-, CD33-, CD56+, CD123+]

See also

 lymphoblastic leukemias

References

 Karube K, Ohshima K, Tsuchiya T, Yamaguchi T, Suefuji H, Suzumiya J, Harada M, Kikuchi M. Non-B, non-T neoplasms with lymphoblast morphology: further clarification and classification. Am J Surg Pathol. 2003 Oct;27(10):1366-74. PMID: #14508398#