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refractory mesial temporal lobe epilepsy

Wednesday 22 March 2017

Hippocampal sclerosis (HS) and focal cortical dysplasia (FCD) are among the most common neuropathological findings in those undergoing surgery for refractory mesial temporal lobe epilepsy (MTLE).

HS subtype does not appear to affect epilepsy surgery outcomes, despite some clinical differences between the subgroups. FCD is often observed in association with HS in MTLE; the finding of FCD was associated with better post-operative outcomes.

Paywall references

- The Role of Histopathologic Subtype in the Setting of Hippocampal Sclerosis-Associated Mesial Temporal Lobe Epilepsy. 2017. doi : 10.1016/j.humpath.2017.02.013