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trifluridine/tipiracil

Tuesday 21 February 2017

WKP

Definition: Trifluridine/tipiracil (trade name Lonsurf) is a combination drug combining trifluridine and tipiracil for the treatment of metastatic colorectal cancer. It is a combination of two active pharmaceutical ingredients: trifluridine, a nucleoside analog, and tipiracil, a thymidine phosphorylase inhibitor. Tipiracil prevents rapid metabolism of trifluridine, increasing the bioavailability of trifluridine.

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