cutaneous lymphomas

Digital cases

 JRC:10597 : cutaneous lymphoma (NOS).
 JRC:10600 : cutaneous lymphoma (NOS).
 JRC:10601 : cutaneous lymphoma (lymphocytic).
 JRC:10603 : cutaneous lymphoma (lymphocytic).
 UI:918 : Mycosis fungoides.
 JRC:10716 : Mycosis fungoides.

Images

 cutaneous anaplastic large cell lymphoma - large atypical cells with mitosis, ALK negative.

• https://twitter.com/JJSpeiserMD/status/742413791825137665

 cutaneous peripheral T cell lymphoma

• https://twitter.com/BellaMicheleang/status/745166666183544832

Types

 primary cutaneous lymphoma

• cutaneous T-cell lymphomas (CTCL)
  • folliculotropic mycosis fungoides
  • Sezary syndrome
  • primary cutaneous CD30+ lymphoproliferative disorders
    • primary cutaneous anaplastic large cell lymphoma
    • lymphomatoid papulosis
    • borderline lesions

• • subcutaneous panniculitis-like T-cell lymphoma
  • primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma
  • primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma
  • cutaneous gamma/delta T-cell lymphoma

• cutaneous B-cell lymphomas
  • primary cutaneous marginal zone B-cell lymphoma (12883238)
  • primary cutaneous follicular centre lymphoma
  • primary cutaneous diffuse large B-cell lymphoma, leg type
  • primary cutaneous diffuse large B-cell lymphoma, other
  • EBV-associated cutaneous B-cell lymphoma

• precursor haematological neoplasms
• CD4+/CD56+ haematodermic neoplasm (early plasmacytoid dendritic cell leukaemia/lymphoma or blastic NK-cell lymphoma )

NB: Provisional entities for updated 2016 WHO classification
 aggressive epidermotropic CD8+ lymphoma
 primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder

• small/medium CD4+ pleomorphic T-cell lymphoproliferative disorder

 indolent CD8+ acral lymphoma

Appearance

 cutaneous large cell lymphomas
 cutaneous small cell lymphomas

See also

 CD4+/CD56+ hematodermic tumors

Open References

 Willemze, R., Jaffe, E.S., Burg, G. et al. WHO-EORTC classification for cutaneous lymphomas. Blood. 2005; 105: 3768–3785.
http://www.bloodjournal.org/content/105/10/3768.long

Paywall References

 Slater DN. The new World Health Organization-European Organization for Research and Treatment of Cancer classification for cutaneous lymphomas: a practical marriage of two giants. Br J Dermatol. 2005 Nov;153(5):874-80. PMID: 16225594