Friday 12 December 2003
Definition: Kaposi sarcoma is a multifocal HHV-8-driven vascular proliferation which does not show conventional features of malignancy—in particular, it may regress spontaneously.
micronodular growth in Kaposi sarcoma
promontory sign in Kaposi sarcoma
Kaposi sarcoma, palate - highlighting fascicular growth (intersecting fascicles )
It shows relative sparing of certain tissues such as brain, kidney and skeletal muscle, is most often diploid, is very difficult to transplant/xenograft and does not appear to show any conventional pattern of metastasis.
Human herpesvirus-8 (HHV-8) infection is considered the initiating factor in all forms of Kaposi sarcoma (KS)
No consistent abnormality