Humpath.com - Human pathology

Home > E. Pathology by systems > Reproductive system > Female genital system > Uterus > endometrial glandular and stromal breakdown

endometrial glandular and stromal breakdown

Friday 13 January 2017

EGBD

Definition: Histopathology of patients with dysfunctional uterine bleeding due to an anovulatory cycle usually contain endometrial glandular and stromal breakdown (EGBD) and papillary metaplasia on the endometrial surface epithelium, if an appropriate sample has been collected.

The appearance of MCIP with condensed stromal clusters originated from the papillary metaplasia, which occurred on the endometrial surface epithelium. The cytologic observation of those cells may be a useful indicator for providing the nature of EGBD endometrium.

Paywall references

- Endometrial glandular and stromal breakdown, part 1: cytomorphological appearance.
Shimizu K, Norimatsu Y, Kobayashi TK, Ogura S, Miyake Y, Ohno E, Sakurai T, Moriya T, Sakurai M.
Diagn Cytopathol. 2006 Sep;34(9):609-13.
PMID: 16900469

- Endometrial glandular and stromal breakdown, part 2: cytomorphology of papillary metaplastic changes.
Norimatsu Y, Shimizu K, Kobayashi TK, Moriya T, Kaku T, Tsukayama C, Miyake Y, Ohno E.
Diagn Cytopathol. 2006 Oct;34(10):665-9.
PMID: 16955472

Portfolio