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keratinocytes

Adj. keratinocytic

Wednesday 3 December 2003

WP

A keratinocyte is the predominant cell type in the epidermis, the outermost layer of the skin, constituting 90% of the cells found there. Those keratinocytes found in the basal layer (stratum basale) of the skin are sometimes referred to as "basal cells" or "basal keratinocytes".

Pathology}

- vacuolated keratinocytes
- dysplastic keratinocytes

  • tumoral keratinocytes

See also

- epidermal basal cells
- corneocytes
- keratin

Videos

- Keratocytes, found on the scales of fish, are specialized for very rapid motility in order to heal scratches."

@<@object width="425" height="350">@<@param name="movie" value="http://www.youtube.com/v/-3SRRwVYAt4">@<@/param>@<@param name="wmode" value="transparent">@<@/param>@<@embed src="http://www.youtube.com/v/-3SRRwVYAt4" type="application/x-shockwave-flash" wmode="transparent" width="425" height="350">@<@/embed>@<@/object>

Ref.: Molecular Biology of the Cell, 4th Edition, by Alerts, Johnson, Lewis. Raff, Roberts, Walter.

References

- Nickoloff BJ. Keratinocytes regain momentum as instigators of cutaneous inflammation. Trends Mol Med. 2006 Mar;12(3):102-6. PMID: 16443394

- Dhitavat J, Fairclough RJ, Hovnanian A, Burge SM. Calcium pumps and keratinocytes: lessons from Darier’s disease and Hailey-Hailey disease. Br J Dermatol. 2004 May;150(5):821-8. PMID: 15149492

- Werner S, Smola H. Paracrine regulation of keratinocyte proliferation and differentiation. Trends Cell Biol. 2001 Apr;11(4):143-6. PMID: 11306276