giant condyloma acuminatum

Definition : Condylomatous squamous lesion without high grade dysplasia, with only low risk HPV types present, forming an exophytic mass, usually greater than 3 cm.

Images

 Giant condyloma acuminatum

• https://twitter.com/DanglisFotiosMD/status/778508686742478848

Associations

 human papillomavirus infection
 immune deficiency
 systemic lupus erythematosus (SLE) (21965277)
 poor sanitary conditions
 multiple sexual partners
 chronic genital infection

Differential diagnosis

 condyloma acuminatum
 verrucous carcinoma
 squamous cell carcinoma (SCC)
 anal squamous papilloma

Recent studies and WHO 2019 have suggested that Buschke-Löwenstein tumors and verrucous carcinoma are 2 separate entities.

While Buschke-Löwenstein tumors are associated with low risk HPV types (HPV6, HPV11), verrucous carcinoma usually has a non-HPV etiology.

See also

 condyloma acuminatum

• condylomatous squamous anomalies / condylomatous squamous lesions