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giant condyloma acuminatum

Wednesday 21 September 2016

Giant condyloma acuminatum ; Buschke-Löwenstein tumor (1925)

PO

Definition : Condylomatous squamous lesion without high grade dysplasia, with only low risk HPV types present, forming an exophytic mass, usually greater than 3 cm.

Images

- Giant condyloma acuminatum

Associations

- human papillomavirus infection
- immune deficiency
- systemic lupus erythematosus (SLE) (21965277)
- poor sanitary conditions
- multiple sexual partners
- chronic genital infection

Differential diagnosis

- condyloma acuminatum
- verrucous carcinoma
- squamous cell carcinoma (SCC)
- anal squamous papilloma

Recent studies and WHO 2019 have suggested that Buschke-Löwenstein tumors and verrucous carcinoma are 2 separate entities.

While Buschke-Löwenstein tumors are associated with low risk HPV types (HPV6, HPV11), verrucous carcinoma usually has a non-HPV etiology.

See also

- condyloma acuminatum