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promontory sign

Monday 13 June 2016

The characteristic appearance of a small vessel protruding into an abnormal vascular space has been termed "promontory sign".

Image

- promontory sign in Kaposi sarcoma

Etiology

- Kaposi sarcoma

  • Kaposi sarcoma is characterized by a proliferation of irregular jagged vascular channels, which partly surround preexisting blood vessels in some areas.

- cutaneous angiosarcoma

  • Cutaneous angiosarcoma (AS) is a malignant vascular neoplasm comprised of a meshwork of anastomosing irregular dilated vessels between collagen bundles and around skin appendages, lined by atypical endothelial cells.
  • The presence of promontory sign can also be described as a histologic finding in AS.

References

- Promontory sign—present in patch and plaque stage of angiosarcoma! Lazova R, McNiff JM, Glusac EJ, Godic A. Am J Dermatopathol. 2009 Apr;31(2):132-6. doi : 10.1097/DAD.0b013e3181951045 PMID: 19318797