post-translational proteic modifications
Sunday 30 November 2003
Post-translational modifications define the functional and structural plasticity of proteins in archaea, prokaryotes and eukaryotes.
Multi-site protein modification modulates protein activity and macromolecular interactions and is involved in a range of fundamental molecular processes.
- O-linked N-acetylglucosamine (GlcNAc) glycosylation
proteic phosphorylation (PO4)
proteic carboxyl methylation by methyltransferase
endoproteolytic processing by protease
Seet BT, Dikic I, Zhou MM, Pawson T. Reading protein modifications with interaction domains. Nat Rev Mol Cell Biol. 2006 Jul;7(7):473-83. PMID: 16829979