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Home > E. Pathology by systems > Skin > eccrine spiradenoma

eccrine spiradenoma

Monday 30 May 2016

Definition: Spiradenoma forms a firm nodule on the face or upper trunk, and can be painful. The lesion is benign. Histologically it shows nests with two types of cells: small hyperchromatic cells at the periphery and larger and paler cells centrally. There is compact PAS+ eosinophilic basement membrane material and infiltrating lymphocytes.


- eccrine spiradenoma

- cystic eccrine spiradenoma

- eccrine spiradenoma nodule in the subcutis


- sharply circumscribed dermal nodule
- circumscribed nodule(s)
- hyaline globules
- light & dark cells
- "blue ball" in dermis
- eosinophilic hyaline droplets
- ducts
- lymphocytes


- malignant eccrine spiradenoma

See also

- cutaneous tumors