Humpath.com - Human pathology

Home > A. Molecular pathology > GNAs

GNAs

Friday 29 April 2016

Examples

GNA11

Guanine nucleotide-binding protein subunit alpha-11 is a protein that in humans is encoded by the GNA11 gene. Together with GNAQ (its paralogue), it functions as a Gq alpha subunit.

Pathology

- GNA11 Mutation in Cutaneous Origin Melanoma (26825879)

- Mosaic Activating Mutations in GNA11 and GNAQ Are Associated with Phakomatosis Pigmentovascularis and Extensive Dermal Melanocytosis. (26778290)

Open references

- GNA11 Mutation in a Patient With Cutaneous Origin Melanoma: A Case Report.
Patel SP, Kim DW, Lacey CL, Hwu P.
Medicine (Baltimore). 2016 Jan;95(4):e2336. doi : 10.1097/MD.0000000000002336
PMID: 26825879

- Mosaic Activating Mutations in GNA11 and GNAQ Are Associated with Phakomatosis Pigmentovascularis and Extensive Dermal Melanocytosis.
Thomas AC, Zeng Z, Rivière JB, O’Shaughnessy R, Al-Olabi L, St-Onge J, Atherton DJ, Aubert H, Bagazgoitia L, Barbarot S, Bourrat E, Chiaverini C, Chong WK, Duffourd Y, Glover M, Groesser L, Hadj-Rabia S, Hamm H, Happle R, Mushtaq I, Lacour JP, Waelchli R, Wobser M, Vabres P, Patton EE, Kinsler VA.
J Invest Dermatol. 2016 Apr;136(4):770-8. doi : 10.1016/j.jid.2015.11.027
PMID: 26778290