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flat urothelial hyperplasia

Wednesday 30 March 2016


Definition: flat urothelial hyperplasia is caracterized by a thickening of the urothelium which still shows orderly maturation to the surface and lacks cytologic atypia.

Flat urothelial hyperplasia may occur de novo, where it appears to have no malignant potential.

It may also be seen in conjuction with cystitis , bladder calculi , and urothelial tumors.

Several fragments/foci should be examined to prevent overdiagnosing a single focus with tangential sectioning as flat hyperplasia.


- thickening of the urothelium
- orderly maturation to the surface
- lack of cytologic atypia


- flat urothelial hyperplasia

See also

- urothelial hyperplasia

- urothelial anomalies