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Wednesday 2 July 2014

TICdb is a database of Translocation breakpoints In Cancer. This update contains 1,374 fusion sequences found in human tumors, involving 431 different genes.

For every fusion, TICdb will return the HGNC name of both partner genes and the original reference (either a GenBank or a Pubmed ID), as well as the fusion sequence.

TICdb team has also developed ONCOFUSE, a bayesian classifier that predicts the oncogenic potential of fusion genes found by NGS.

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