CTCs competence for metastasis
Sunday 5 January 2014
CTCs competent for metastasis
- The identification and characterization of breast cancer CTCs competent for brain metastasis. (23576814)
- Brain metastatic breast cancer (BMBC) is uniformly fatal and increasing in frequency.
- Despite its devastating outcome, mechanisms causing BMBC remain largely unknown. The mechanisms that implicate circulating tumor cells (CTCs) in metastatic disease, notably in BMBC, remain elusive.
Interplay of Stem Cell Characteristics, EMT, and Microtentacles in Circulating Breast Tumor Cells. Charpentier M, Martin S. Cancers (Basel). 2013 Nov 14;5(4):1545-65. doi : 10.3390/cancers5041545 PMID: 24240660 [Free]
MicroRNA and protein profiling of brain metastasis competent cell-derived exosomes. Camacho L, Guerrero P, Marchetti D. PLoS One. 2013 Sep 16;8(9):e73790. doi : 10.1371/journal.pone.0073790. eCollection 2013 PMID: 24066071 [Free]
The identification and characterization of breast cancer CTCs competent for brain metastasis. Zhang L, Ridgway LD, Wetzel MD, Ngo J, Yin W, Kumar D, Goodman JC, Groves MD, Marchetti D. Sci Transl Med. 2013 Apr 10;5(180):180ra48. doi : 10.1126/scitranslmed.3005109 PMID: 23576814 [Free]