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cardiovascular Behçet disease

Monday 16 September 2013

Cardiac Behçet disease

Behçet disease is an inflammatory disorder of unknown etiology showing diverse clinical presentations. Cardiac involvement is a critical problem that requires a timely diagnosis and management. Cardiac Behçet disease is presented as aortic valvulitis/aortitis or inflammatory mass lesion.

Synopsis

- severe aortic regurgitation with redundant prolapsing aortic cusps
- irregular mass lesions in the right ventricular cavity
- The aortic root is also involved with aortic valvulitis, showing severe mixed acute and chronic inflammation of various stages.
- There are frequent microabscess and extensive endothelial loss with fibrinous deposit.
- The right heart lesions shows similar histopathologic features

References

- Cardiac Behçet disease presenting as aortic valvulitis/aortitis or right heart inflammatory mass: a clinicopathologic study of 12 cases. Lee I, Park S, Hwang I, Kim MJ, Nah SS, Yoo B, Song JK. Am J Surg Pathol. 2008 Mar;32(3):390-8. doi: 10.1097/PAS.0b013e31814b23da. PMID: #18300812#