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monitoring drug resistance by cell-free DNA

Tuesday 24 September 2013

Monitoring of acquired resistance to cancer therapy; monitoring acquired resistance to cancer therapy in plasma cell-free DNA

References

- Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Murtaza M, Dawson SJ, Tsui DW, Gale D, Forshew T, Piskorz AM, Parkinson C, Chin SF, Kingsbury Z, Wong AS, Marass F, Humphray S, Hadfield J, Bentley D, Chin TM, Brenton JD, Caldas C, Rosenfeld N. Nature. 2013 May 2;497(7447):108-12. doi: 10.1038/nature12065 . PMID: #23563269#

- Detection of EGFR T790M mutation in plasma DNA from patients refractory to EGFR tyrosine kinase inhibitor. Sakai K, Horiike A, Irwin DL, Kudo K, Fujita Y, Tanimoto A, Sakatani T, Saito R, Kaburaki K, Yanagitani N, Ohyanagi F, Nishio M, Nishio K. Cancer Sci. 2013 May 31. doi: 10.1111/cas.12211. PMID: #23721103#