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T1 oral squamous cell carcinoma

Tuesday 23 September 2014

Prognosis

- Perineural invasion (PNI) has been recognized as a poor prognostic factor for Oral Squamous Cell Carcinoma.

  • PNI independently predicts a poor prognosis in T1 Oral Squamous Cell Carcinoma patients who are potentially curable but tend to be treated conservatively.
  • For its efficacy in improving treatment outcomes, aggressive elective neck dissection (END) is indicated for T1 Oral Squamous Cell Carcinoma (OSCC) patients at the presence of PNI.

References

- Perineural Invasion in T1 Oral Squamous Cell Carcinoma Indicates the Need for Aggressive Elective Neck Dissection. Tai SK, Li WY, Yang MH, Chu PY, Wang YF. Am J Surg Pathol. 2013 May 15. PMID: 23681077