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pleural effusion

Friday 17 May 2013


- inflammatory pleural effusion

  • neutrophilic pleural effusion
  • eosinophilic pleural effusion
  • lymphocytic pleural effusion
  • histiocytic pleural effusion

- tumoral pleural effusion


- drug-induced pleural effusion (drug-induced pleural exudate)

  • lone non-eosinophilic pleural effusion
  • lone eosinophilic pleural effusion
  • pleural effusion associated with drug-induced pneumonitis
  • drug-induced lupus erythematosus (DILE)
  • drug-induced pleural thickening
    • irradiation
    • amiodarone
    • ergolines
    • chemotherapeutic agents (cyclophosphamid)
    • practolol
    • corticosteroids

- asbestos-associated fibrinous pleural effusion
- pulmonary edema
- pulmonary capillary leak syndrome


- Pleural disease, 2nd edition. Bouros D. et al.

See also

- pleural anomalies
- pleural diseases

Open references

- Immunohistochemical distinction between mesothelial and adenocarcinoma cells in serous effusions: a combination panel-based approach with a brief review of the literature. Murugan P, Siddaraju N, Habeebullah S, Basu D. Indian J Pathol Microbiol. 2009 Apr-Jun;52(2):175-81. PMID: 19332905 (Free)


- Diagnostic usefulness of EMA, IMP3, and GLUT-1 for the immunocytochemical distinction of malignant cells from reactive mesothelial cells in effusion cytology using cytospin preparations. Ikeda K, Tate G, Suzuki T, Kitamura T, Mitsuya T. Diagn Cytopathol. 2011 Jun;39(6):395-401. doi : 10.1002/dc.21398 PMID: 21574259

- The use of immunohistochemistry to distinguish reactive mesothelial cells from malignant mesothelioma in cytologic effusions. Hasteh F, Lin GY, Weidner N, Michael CW. Cancer Cytopathol. 2010 Apr 25;118(2):90-6. doi : 10.1002/cncy.20071 PMID: 20209622

- Immunohistochemical panel for distinguishing between carcinoma and reactive mesothelial cells in serious effusions. Lee JS, Nam JH, Lee MC, Park CS, Juhng SW. Acta Cytol. 1996 Jul-Aug;40(4):631-6. PMID: 8693877

- Significance of epithelial membrane antigen in the work-up of problematic serous effusions. Singh HK, Silverman JF, Berns L, Haddad MG, Park HK. Diagn Cytopathol. 1995 Jul;13(1):3-7. PMID: 7587872

- Assessment of immunocytochemical and histochemical stainings in the distinction between reactive mesothelial cells and adenocarcinoma cells in body effusions. Chen CJ, Chang SC, Tseng HH. Zhonghua Yi Xue Za Zhi (Taipei). 1994 Sep;54(3):149-55. PMID: 7954054

- Markers for metastatic adenocarcinoma in serous effusion specimens. Shield PW, Callan JJ, Devine PL. Diagn Cytopathol. 1994;11(3):237-45. PMID: 7532566